Drawing on findings from hundreds of peer-reviewed studies, Dr. Marik and his team developed a monograph intended to educate physicians and patients about the often-overlooked role repurposed medications, supplements, and lifestyle habits can play in cancer treatment protocols. 

The Role of Repurposed Drugs and Metabolic Interventions in Treating Cancer (2nd Edition, 2024) — a 257-page comprehensive guide that reviews over 1,300 studies and presents a tiered system of repurposed drugs, lifestyle changes, and supportive strategies. The protocol is positioned as adjunctive care, aimed at improving quality of life, reducing chemotherapy toxicity, and supporting standard treatments such as surgery, chemotherapy, and radiation.

The protocol features key compounds including ivermectin, mebendazole, doxycycline, and curcumin as Tier 1 agents, alongside Tier 2 agents such as atorvastatin, metformin, melatonin, zinc, and Vitamin D3 — all used as an adjunct to standard oncology care rather than a replacement. [The Fenbendazole]

The goal of Cancer Care is to provide a well-researched clearinghouse of information that picks up where traditional cancer therapies leave off, giving providers the tools to think creatively about readily available interventions backed by science that could improve patient outcomes.

The First Edition of Cancer Care ranked #118 out of more than 50,000 cancer books on Amazon and #35 in Medical Research. It became a trusted resource for nearly 15,000 readers on Amazon and was accessed by more than 200,000 people through the FLCCC website — a testament to the enormous demand for this type of integrative oncology guidance.

 

Education & Early Training

Dr. Marik received his medical degree from the University of the Witwatersrand in Johannesburg, South Africa, where he also served as an ICU attending at Baragwanath Hospital in Soweto. During this period, he earned a Master of Medicine degree, a Bachelor of Science in Pharmacology, a Diploma in Anesthesia, and a Diploma in Tropical Medicine and Hygiene.

Before completing his formal training, Dr. Marik served as an Army doctor during the Cuban intervention in Angola — treating injured soldiers and local civilians, sometimes seeing up to 200 patients a day — an experience he describes as “invaluable training.” 

He went on to complete a Critical Care Fellowship in London, Ontario, Canada, during which he was admitted as a Fellow to the Royal College of Physicians and Surgeons of Canada, and has worked in various teaching hospitals across the United States since 1992.

 

Board Certifications & Specializations

Dr. Marik is board certified in Internal Medicine, Critical Care Medicine, Neurocritical Care, and Nutrition Science.  His medical expertise spans a remarkably diverse set of fields, including Internal Medicine, Critical Care, Neurocritical Care, Pharmacology, Anesthesia, Nutrition, and Tropical Medicine and Hygiene. 

 

Academic Career

Dr. Marik joined Eastern Virginia Medical School (EVMS) in 2009, where he held the positions of Professor of Medicine and Chief of Pulmonary and Critical Care Medicine, and also maintained privileges in the intensive care unit at Sentara Norfolk General Hospital in Virginia. 

He received numerous teaching awards throughout his career, including the prestigious National Teacher of the Year award from the American College of Physicians in 2017. 

 

Research & Publications

Dr. Marik has authored over 500 peer-reviewed journal articles, 80 book chapters, four critical care books, and the Cancer Care Monograph — earning him the distinction of being the second most published critical care physician in the world. 

His H-Index of 111 places him among the top percentile of the world’s elite published physicians, and he has been widely recognized as the most published and influential clinician and researcher in critical care medicine in the United States. 

Revolutionary Work in Sepsis

Dr. Marik is also renowned for his revolutionary work in developing a lifesaving protocol for sepsis, a condition responsible for more than 250,000 deaths annually in the U.S. alone.

His intravenous Vitamin C protocol, known as HAT (Hydrocortisone, Ascorbic Acid, and Thiamine), garnered massive international attention, with over 1,100 reports from physicians around the world noting remarkable results in septic shock patients. Medicare statistics at his hospital recorded a drop in the death rate of sepsis patients from 22% to 6% in the year following implementation of the protocol. 

COVID-19 Protocols & The FLCCC Alliance

In January 2020, Dr. Marik established a COVID-19 hospital treatment protocol (the EVMS protocol), based on his effective treatment protocol for sepsis. Through collaboration with international colleagues, this approach was further developed into the MATH+ Hospital Treatment, I-MASK+ Prevention & Early Outpatient Treatment, and I-RECOVER Management protocols. 

In January 2022, Dr. Marik retired from EVMS to focus on his leadership of the Front Line COVID-19 Critical Care Alliance (FLCCC), where he has co-authored more than 10 papers on therapeutic approaches to treating COVID-19.

 

Recognition & Honors

In March 2022, Dr. Marik received a commendation by unanimous vote of the Virginia House of Delegates for his courageous treatment of critically ill COVID-19 patients and his philanthropic efforts to share effective treatment protocols with physicians around the world.